VENTILATOR ASSOCIATED PNEUMONIA; PREVALENCE AND MICROBIAL PATTERNS

Ajeet Kumar, M. Ishaq Ghauri, Salma Razzaque, Asifa Jamali, Jibran Suahleh Mohammad

Abstract


Objective: The Study was designed to determine prevalence of Ventilator Associated Pneumonia (VAP) and to identify the commonest pathogens responsible, in a tertiary care hospital located at sub-urb industrial region of Karachi, Pakistan.
Methods: A prospective cross-sectional study was conducted in ICU at JMCH, Korangi Karachi from Jan 2012 to Jan 2013. Patients, who received mechanical ventilation > 48 hours, were prospectively followed for occurrence of VAP. The clinical diagnosis of VAP was made on the basis of CPIS criteria and confirmed by quantitative culture of tracheal secretion.
RESULT: 275 patients meeting inclusion criteria were included in the study, out of which 84 (30.5%) developed VAP. The common pathogens were Pseudomonas aeruginosa (63%), Acinetobacter lwoffi (22%) and Staphylococcus aureus (33%). Increased ICU stay and over all mortality (59.5%) was observed in VAP group.
Conclusion: The frequency of VAP in our ICU was comparable to other settings in our region, most common pathogens are gram negative bacilli which showed resistance to many antibiotics. Mortality was high in patients developing VAP when compared to patient on ventilator not developing pneumonia.


Keywords


Ventilator-aasociated Pneumonia; Nosocomial Pneumonia; Gram negative bacilli.

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