SEPSIS AND SEPTIC SHOCK: UPDATES

Abstract

Sepsis, severe sepsis and septic shock are a spectrum which occurs in response to an infection. They are associated with a high degree of morbidity and mortality. This article reviews the definitions, pathophysiology and management of sepsis. In particular, measures to achieve adequate tissue perfusion and oxygenation, as outlined by the updated 2012 Surviving Sepsis Campaign, are discussed.