Radiological manifestations of Granulomatosis with Polyangiitis

Authors

  • Javaid Khan Aga Khan University Hospital
  • Zain Khan Aga Khan University Hospital
  • Amala Khan Aga Khan University Hospital
  • Muhammad Mehdi Aga Khan University Hospital

Keywords:

vasculitis, wegeners, granulomatosis, polyangiitis, radiological features, ANCA, chest xray,

Abstract

Wegener's granulomatosis (Granulomatosis with Polyangiitis) is a small vessel vasculitis that can affect any organ system but mainly effects the respiratory tract and kidneys. It is diagnosed by a combination of clinical features, lab investigations, radiological findings and biopsy from a relevant organ. There is a strong association of Wegener's granulomatosis with C-ANCA levels ( cytoplasmic-antineutrophil cytoplasmic anyibodies). Early diagnosis is critical, as it gives the patient the best chance of remission with cytotoxix therapy. In this case series, the authors present six different radiological presentations of Granulomatosis with Polyangiitis, illustrating the need to include this disease in the differential diagnosis in such cases.

Author Biographies

Javaid Khan, Aga Khan University Hospital

Professor of Chest MedicineDepartment of Pulmonology and critical care

Zain Khan, Aga Khan University Hospital

Resident (PGY1)Department of Internal Medicine

Amala Khan, Aga Khan University Hospital

Intern year 2020

Muhammad Mehdi, Aga Khan University Hospital

Intern year 2020

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Published

2021-08-10

How to Cite

Khan, J., Khan, Z., Khan, A., & Mehdi, M. (2021). Radiological manifestations of Granulomatosis with Polyangiitis. Pakistan Journal of Chest Medicine, 27(1), 37–41. Retrieved from https://pjcm.net/index.php/pjcm/article/view/675

Issue

Section

Case Report