Incidence and Impact of Gynecological Disorders in Women Undergoing Multi-Drug Resistant Tuberculosis (MDR-TB) Treatment

Abstract

Background: Treatment for Multi-Drug Resistant Tuberculosis (MDR-TB) is costly, time-consuming, and ineffective. It could cause damage to pregnant women and their babies during the pregnancy. Objective: To explore the frequency of gynecological problems in women on MDR tuberculosis treatment Methodology: The current cross-sectional study was conducted at the Department of Gynecology DHQ hospital Narowal from august 2019 to October 2020 after taking permission from the ethical committee of the institute. A total of 240 women diagnosed with MDR-TB aged 15 to 54 years without children were included in this study while individuals with Hysterectomy and salpingo-oophorectomy were excluded. All the information we got was with consent. Everyone spoke. The online G-power tool used to create a 95% confidence interval. Qualitative data was calculated by IBM SPSS version 24. Ethical certificate was taken from ethical committee of the DHQ hospital Narowal. Results: The present study included 240 participants in total, ranging in age from 15 to 54 years.  Individuals between the ages of 15 and 24 were 56 (23.3%), between the ages of 25 and 34 were 97 (40.4%), between the ages of 35 and 44 were 70 (29.1%) and between the ages of 45 and 54 were 17(7%). Among study cases, 194 (80%) were premenopausal and 34 (14.1%) was post-menopausal. Individuals with MDR-TB therapy had high prevalence   of itchy and irritated vaginal discharge ((65%) and 34.16%) correspondingly). Four commonly prescribed contraceptives were explored. Among study cases,10 (4.1%) of women used I.U.D.s, 11.4% oral contraceptives, 29.5% injectable and 54.58% barrier approaches. The occurrence of ploy menorrhagia and olig-menorrhagia in women getting MDR-TB treatment   is 40.8% and 59.1%, correspondingly. Conclusion: The study concluded that patients with MDR-TB experienced gynecological problems. MDR-TB premenopausal patients experienced polymenorrhea, dysmenorrhea, and irregular menstruation and menorrhagia.