TREATMENT OUTCOME OF MULTI-DRUG RESISTANT TUBERCULOSIS (MDR-TB)

Abstract

OBJECTIVE: To assess the treatment outcome of multi-drug resistant tuberculosis (MDR-TB).PLACE AND DURATION: People’s University and Medical Health Sciences,Nawabshah during the period of four years from January 2007 to December2010.MATERIAL AND METHOD: Patients were selected from Pulmonology outpatientdepartment and ward, after having confirmed MDR-TB by Laboratory AFBculture and DST (Drug Sensitivity Test). Patients were admitted in Pulmonologyward till sputum conversion was achieved. The details of demographic data,chemotherapy, adverse reactions to drugs, follow-up assessment as well asregular sputum bacteriology and chest radiograph result were recorded.Medical records were reviewed of patients treated for MDR-TB from January2007 to 2010 and monitored three years after initiation of treatment. Initial treatment outcomes and survival rates were analyzed.RESULTS: 14 out of 36 patients (38.44%) treatment success rate was found atthe end of treatment and 8 patients (22.24%) were failed to achieved sputumconversion by smear and culture at the end of MDR-TB treatment. Where aseight patients (22.24%) were defaulter and 4 patients (11.22%) were died and 2 patients (5.56%) were relapsed after completing their treatment.CONCLUSION: Adequate TB control polices should be implemented to preventthe further spread of drug resistance.