Exploring the Interplay between Respiratory and Periodontal Health in Adults Undergoing Orthodontic Therapy: Insights from a Tertiary Care Hospital

Authors

  • Sakina Qazi Department of Periodontology, University Medical and Dental College, Faisalabad - Pakistan
  • Sadia Nisar Ahmed Department of Orthodontics, Bacha Khan Medical College, Mardan – Pakistan
  • Sana Mukhtar Department of Periodontology, Foundation University, College of Dentistry, Islamabad – Pakistan
  • Syed Shahan Haider Department of Periodontology, Dental College HITEC - IMS, Wah Cant. – Pakistan
  • Muhammad Harris Abdullah Islamic International Dental College, Islamabad - Pakistan
  • Ayesha Khalil University Medical and Dental College, Islamabad - Pakistan

DOI:

https://doi.org/10.1996/pjcm.v29i2.843

Keywords:

Periodontitis, Respiratory Exacerbations, Hospitalizations, Oral Health, Respiratory Outcomes

Abstract

Background: In the realm of healthcare, the intricate interplay between respiratory health and periodontal health in adults has garnered considerable attention in recent years. The intricate relationship between these seemingly distinct domains lies in the common thread of inflammation. Both respiratory diseases and periodontal conditions, such as chronic obstructive pulmonary disease (COPD) and periodontitis, are characterized by chronic inflammation. Emerging research suggests that this shared inflammatory pathway may contribute to a bidirectional relationship, where respiratory diseases can exacerbate periodontal conditions, and vice versa.   Objective: The present study was performed with the aim of investigating the relationship between periodontal health and respiratory diseases.   Methodology: Data were analyzed from 82 participants, categorized into two groups based on their periodontitis status: Absent (33 participants, 40.20%) and Present (49 participants, 59.80%). Respiratory outcomes were assessed through self-reported exacerbations and hospitalizations.   Results: The presented data focuses on respiratory exacerbations and hospitalizations, categorizing participants based on the frequency of occurrences. In terms of respiratory exacerbations, participants are divided into three groups: low frequency (29 participants), moderate frequency (32 participants), and high frequency (21 participants). The low-frequency group exhibits a mean exacerbation rate of 0.80%, with a standard deviation of 0.30%, ranging from 0.00% to 1.20%. The moderate-frequency group shows a mean rate of 1.50%, a standard deviation of 0.40%, and a range from 1.00% to 1.90%. For the high-frequency group, participants have a mean exacerbation rate of 2.70%, a standard deviation of 0.60%, and a range from 2.00% to 3.10%.   Conclusion: The present study suggests a potential correlation between the presence of periodontitis and an increased likelihood of experiencing respiratory issues, highlighting the importance of oral health in respiratory health management.

References

Zar HJ, Ferkol TW. The global burden of respiratory disease—impact on child health. Pediatr Pulmonol. 2014;49(5):430-4.

Bansal M, Khatri M, Taneja V. Potential role of periodontal infection in respiratory diseases-a review. J Med Life. 2013;6(3):244.

Ferkol T, Schraufnagel D. The global burden of respiratory disease. Ann Am Thorac Soc. 2014;11(3):404-6.

Scannapieco FA, Ho AW. Potential associations between chronic respiratory disease and periodontal disease: analysis of National Health and Nutrition Examination Survey III. J Periodontol. 2001;72(1):50-6.

Kinane DF, Stathopoulou PG, Papapanou PN. Periodontal diseases. Nat Rev Dis Primers. 2013;3(1):1-4.

Parashar P, Parashar A, Saraswat N, Pani P, Pani N, Joshi S. Relationship between respiratory and periodontal health in adults: A case–control study. J Int Soc Prev Community Dent. 2018;8(6):560.

Kouanda B, Sattar Z, Geraghty P. Periodontal Diseases: Major Exacerbators of Pulmonary Diseases? Pulmonary Med. 2021; 4712406:1-10.

Ramesh A, Varghese SS, Jayakumar ND, Malaiappan S. Chronic obstructive pulmonary disease and periodontitis–unwinding their linking mechanisms. Oral Biosci.2016;58(1):23-6.

Van Eeden SF, Sin DD. Chronic obstructive pulmonary disease: a chronic systemic inflammatory disease. Respirat. 2008;75(2):224-38.

Nagpal R, Yamashiro Y, Izumi Y. The two-way association of periodontal infection with systemic disorders: an overview. Mediat Inflam. 2015; 793898.

Infused AA. Southern Regional Meeting Abstracts. J Investig Med. 2014;62(2):409.

Rasheed A, Noor M, Usman T, Bilqees R, Afnan M, Gul S, Khan NU, Khattak S, Khattak I, Shah AA. Drugs being tested against COVID-19 to slow down its spread and find effective treatment: A systematic review. Int J Endorsing Health Sci Res. 2022;10(2):255-72.

Apessos I, Voulgaris A, Agrafiotis M, Andreadis D, Steiropoulos P. Effect of periodontal therapy on COPD outcomes: a systematic review. BMC Pulm Med. 2021;21(1):1-6.

Herzog R, Cunninghamâ€Rundles S. Pediatric asthma: natural history, assessment, and treatment. Mt Sinai J. 2011;78(5):645-60.

Oliva IB, Cortopassi F, Herzog EL, Rubinowitz AN. Clinical and Imaging Features of Bronchiectasis. Clin Pulm Med. 2013;20(5):203-13.

Adler D, Pepin JL, Dupuis-Lozeron E, Espa-Cervena K, Merlet-Violet R, Muller H, Janssens JP, Brochard L. Comorbidities and subgroups of patients surviving severe acute hypercapnic respiratory failure in the intensive care unit. Am J Respir Crit Care Med. 2017;196(2):200-7.

Brock M, Bahammam S, Sima C. The relationships among periodontitis, pneumonia and COVID-19. Front Oral Health. 2022;2:801815.

Global Initiative for Chronic Obstructive Pulmonary Disease. 2018. Available from URL: https:// goldcopd.org/wp-content/ uploads/ 2017/ 11/GOLD-2018-v6.0-FINAL-revised-20-Nov_WMS.pdf

Sharma G, Mahler DA, Mayorga VM, Deering KL, Harshaw Q, Ganapathy V. Prevalence of low peak inspiratory flow rate at discharge in patients hospitalized for COPD exacerbationChronic Obstr Pulm Dis.2017;4(3):217.

Nikitakis NG, Papaioannou W, Sakkas LI, Kousvelari E. The autoimmunity–oral microbiome connection. Oral Dis. 2017;23(7):828-39.

Han W, Su Y, Liu B, Zhu W, Yu X, Sun X, et al. Association between hospitalizations for asthma exacerbation and weather conditions in Qingdao: an ecological study. J Transl Med. 2022;10(7):420.

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Published

2023-06-02

How to Cite

Sakina Qazi, Sadia Nisar Ahmed, Sana Mukhtar, Syed Shahan Haider, Muhammad Harris Abdullah, & Ayesha Khalil. (2023). Exploring the Interplay between Respiratory and Periodontal Health in Adults Undergoing Orthodontic Therapy: Insights from a Tertiary Care Hospital. Pakistan Journal of Chest Medicine, 29(2), 199–207. https://doi.org/10.1996/pjcm.v29i2.843

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Original Article